国产泮托拉唑等三联疗法根除幽门螺杆菌

目的：观察国产泮托拉唑、胶体果胶铋(CBP)和呋喃唑酮三联疗法根除幽门螺杆菌(Hp)的疗效及不良反应。方法：把确诊为Hp感染的60例消化性溃疡(PU)病人随机分为2组，A组32例给予泮托拉唑、CBP和呋喃唑酮治疗。B组28例给予奥美拉唑、克拉霉素和甲硝唑治疗。2组疗程均14d。治疗期间分别观察2组药物不良反应。结果：A组Hp根除率为93．5％，B组92．8％，无显著性差异。而不良反应发生率A组明显少于B组。结论：使用A组药物治疗Hp感染的PU，疗效肯定，不良反应少。

Triple Therapy with Domestic Pantoprazole and Others for Eradication of Helicobacter Pylori

Objective: To observe the effects and adverse reactions of triple therapy with pantoprazole, colloid bismuth subcitrate(CBP)and furazolidone for eradication of Helicobacter pylori (Hp). Method: 60 cases of peptic ulcer with Hp infection were randomly divided into 2 groups. 32 cases in group A were given pantoprazole, CBP, and funazolidone with Hpinfection. 28 cases in group B were given omeprazole, clarithromycin, and metronidazole. 2 groups were treated for 14 days.Drug adverse reactions were observed during the treatment. Result: The Hp eradication rate of Hp in group A was 93.5% ,and group B was 92.8% .There was no significant difference between 2 groups,while the adverse reactions were fewer and the price is lower in group A than in group B. Conclusion: Group A has high effect but low adverse reaction incidence for peptic ulcer caused by Hp.