比较群体化疗和目标化疗在较高感染率水平的成本─效果研究

在枞阳县凤仪乡选择感染率在12％左右的2组人群，分别实施群体化疗方案（A组）和目标化疗方案（B组），对其防治效果及实施成本进行了对比观察和分析。结果：连续实施2年，2组人群感染率分别下降69．37％和56．75％（P＞0．05）；实施成本分别为14．26元／人均和9．70元／人均；而单位效果成本，第1年B组是A组的1．4倍，第2年A组则是B组的1．8倍。提示在较高感染率水平（12％以上）的人群中宜采用群体化疗方案，而当其感染率水平降低到一定程度（8％以下）时，则应改用目标化疗方案。

COMPARISON OF THE COST-EFFECTIVENESS BETWEEN MASS CHEMOTHERAPY AND SELECTIVE POPULATION CHEMOTHERAPY IN AREAS WITH HIGER INFECTION OF SCHISTOSOMIASIS

This paper reported the cost-effectiveness of mass chemotherapy and selective population chemotherapy used in areas with higher infection of schistosomiasis for two years. The results showed that the effectiveness of two kinds of chemotherapy was no difference significantly. The unit cost of effectiveness in mass chemotherapy was higher than that in selective population chemotherapy in the first year,but in the second year it was reversed. It is suggested that mass chemotherapy is better used in areas with higher infection (the infection rate was about 12%) of schistosomiasis and selective population chemotherapy is used in areas with lower infection (the infection rate was about 8%).