肺癌化疗患者癌因性疲乏及其对生活质量的影响分析

目的 了解肺癌化疗患者癌因性疲乏的发生率和严重程度,分析肺癌化疗患者癌囚性疲乏与生活质量的相关性.方法 采用横断面调查研究方法,应用Piper疲乏量表和简明健康测量量表(SF-36)对72例肺癌化疗患者进行问卷调查.结果 肺癌化疗患者疲乏的发生率为76.4%,整体疲乏和行为/严重性、情感、感觉等维度的中重度疲乏发生率分别为68.1%、63.9%、76.4%、65.3%,认知/情绪维度的轻中度疲乏发生率为41.7%,疲乏得分排序为情感维度＞行为俨重性维度＞感觉维度＞认知/情绪维度.肺癌化疗患者的癌因性疲乏与生活质量在多个维度上呈显著负相关.结论 肺癌化疗患者癌因性疲乏的发生率较高、程度较重,疲乏与生活质量两者相互影响,应采取减轻疲乏的干预措施,以提高肺癌化疗患者的生活质量.

Study on cancer-related fatigue of lung cancer patients receiving chemotherapy and its impact on the quality of life

Objective To explore the incidence and severity of cancer-related fatigue (CRF),and to analyze the correlation between CRF and quality of life in lung cancer patients receiving chemotherapy.Methods This was a cross-sectional study.72 lung cancer patients receiving chemotherapy were investigated by the Piper Fatigue Scale (PFS) and the 36-item short form of the Medical Outcomes Study questionnaire (SF-36).Results The rate of fatigue for lung cancer patients receiving chemotherapy was 76.4%.The incidence of moderate and severe fatigue in total fatigue,behavior/severity dimension,affective dimension,sensory dimension was 68.1%,63.9%,76.4% and 65.3% respectively.The incidence of mild and moderate fatigue in coguitive/mood dimension was 41.7%.The fatigue dimension scores ranked in a descending order,affective,behavior/severity,sensory and cognitive/mood.There was significant negative correlation between CRF and quality of life for lung cancer patients receiving chemotherapy.Conclusions In lung cancer patients receiving chemotherapy,the incidence and degree of fatigue was high.CRF and QOL affect each other.The health care providers should take measures to alleviate lung cancer patients' fatigue in order to improve the QOL of them.