| 乌司他丁对腮腺良性肿瘤切除术病人炎性相关细胞因子影响 |
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| 引用本文： | 刘霞,郑雪松.乌司他丁对腮腺良性肿瘤切除术病人炎性相关细胞因子影响[J].齐鲁医学杂志,2010,25(2):125-126,129. |
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| 作者姓名： | 刘霞 郑雪松 |
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| 作者单位： | 1. 栖霞市人民医院口腔科,山东,栖霞,265300
2. 栖霞市人民医院泌尿外科,山东,栖霞,265300 |
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| 摘 要： | 目的探讨鸟司他丁对腮腺良性肿瘤切除术病人炎性相关细胞因子的影响。方法将40例全麻下行腮腺良性肿瘤切除术病人随机分为乌司他丁组和对照组（各20例），乌司他丁组于麻醉给药前及术后1d各静滴乌司他丁20万单位，检测并比较两组病人麻醉给药前（T0）、术后30min（T1）、术后60min（T2）、术后90min（T3）、术后1d（T4）时白细胞介素-6（IL-6）、白细胞介素-8（IL-8）、白细胞介素-10（IL-10）水平。结果乌司他丁组T1、T2、T3时IL-6、IL-8检测值较对照组明显降低，IL-10检测值明显高于对照组，差异均有显著性（F=2．63～3．29，P〈0．05）。结论乌司他丁能有效改善体内炎性细胞因子的平衡．对机体手术创伤有明显的防御作用．
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| 关 键 词： | 乌司他丁 腮腺肿瘤 细胞因子类 手术后期间 |
EFFECTS OF ULINASTATIN ON INFLAMMATORY CYTOKINES IN PATIENTS UNDERGOING SURGERY FOR BENIGN TUMOR OF PAROTID |
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| LIU XIA,ZHENG XUE-SONG.EFFECTS OF ULINASTATIN ON INFLAMMATORY CYTOKINES IN PATIENTS UNDERGOING SURGERY FOR BENIGN TUMOR OF PAROTID[J].Medical Journal of Qilu,2010,25(2):125-126,129. |
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| Authors: | LIU XIA ZHENG XUE-SONG |
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| Institution: | LIU XIA,ZHENG XUE-SONG(Department of Stomatology,The People\'s Hospital of Qixia,Qixia 265300,China) |
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| Abstract: | Objective To study the effect of ulinastatin on inflammatory cytokines in patients undergoing surgery for benign parotid tumo. Methods Fourty patients undergoing the operation under general anesthesia were equally randomized to ulinastatin group and control group.Intravenous drip of ulinastatin,200 000 U,was given to those in ulinastatin group,one day before and after surgery.Serum levels of IL-6,IL-8 and IL-10 were detected in both groups before anesthetic was offered(T0),and 30(T1),60(T2),90(T3) min and 2... |
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| Keywords: | ulinastatinl parotid neoplasms cytokine postoperative period |
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