Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase |
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| Authors: | Ho Siaw Eng Subramaniam Geetha Palasubramaniam Selvi Navaratnam Parasakthi |
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| Affiliation: | Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. |
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| Abstract: | We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant. |
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