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Graves'病突眼患者血清抗眼肌抗体的观察
引用本文:余玉洪,余玉洪.Graves'病突眼患者血清抗眼肌抗体的观察[J].现代诊断与治疗,1997,8(2):81-82.
作者姓名:余玉洪  余玉洪
作者单位:福建南平解放军第92医院
摘    要:目的探讨抗眼肌抗体对Graves'病突眼的诊断价值。方法用牛眼肌细胞膜蛋白为抗原,建立酶联免疫吸附试验(ELISA)检测48例健康对照和74例Graves'病突眼患者血清中抗眼肌抗体。结果Graves'病突眼患者血清中抗眼肌抗体的阳性率为68.9%(51/74),对照组抗眼肌抗体阳性率为2.1%(1/48),两组之间有显著性差异(P<0.01)。本法批内误差变异系数(CV)为5.8%~9.6%,批间误差CV为7.3%~10.8%。结论抗眼肌抗体的检测有助于Graves'病突眼的诊断。

关 键 词:抗眼肌抗体  Graves'病  突眼  血清

Observation of Anti eyemuscle Antibodies in Serum of Patients with Graves Ophthalmopathy
Chen Jindi,Yu Yuhong,Wang Xiaoping,Xu Xinshu.Observation of Anti eyemuscle Antibodies in Serum of Patients with Graves Ophthalmopathy[J].Modern Diagnosis & Treatment,1997,8(2):81-82.
Authors:Chen Jindi  Yu Yuhong  Wang Xiaoping  Xu Xinshu
Abstract:Objective\ To investigate the diagnostic value of anti eyemuscle antibodies to Graves ophthalmopathy.Method\ Using antigens from cytomembrane protein of bovine orbitalismuscles,enzyme linked immunosorbent assay(ELISA) was established for determination of serum anti eyemuscle antibodies in 48 health control and 74 patients with Graves ophthalmopathy.Results\ The positive rates of anti eyemuscle antibodies in patients group and control group were 68.9%(51/74) and 2.1%(1/48) respectively.There was a significantly difference between control group and patients group(P<0.01)。The intraassay and interassay coefficients of this assay were 5.8%~9.6% and 7.3%~10.8% respectively.Conclusions\ The detection of anti eyemuscle antibodies is helpful to diagnose Graves ophthalmopathy.
Keywords:Anti  eyemuscle antibodies\ Graves diseaase\ Ophthalmopathy\ Serum
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