| 乳腺基底细胞样癌的临床病理特征 |
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| 引用本文： | 余昶,倪型灏. 乳腺基底细胞样癌的临床病理特征[J]. 肿瘤研究与临床, 2009, 21(4): 282-285. DOI: 10.3760/cma.j.issn.1006-9801.2009.04.027 |
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| 作者姓名： | 余昶 倪型灏 |
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| 作者单位： | 浙江省肿瘤医院病理科,杭州,310022 |
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| 摘 要： | 乳腺基底细胞样癌（BLBC）是根据基因表达模式分离出的一类乳腺癌亚型，具有独特的组织学形态及生物学行为。这类肿瘤通常呈三联阴性（TG）且表达基底细胞型细胞角蛋白（basal CK），侵袭性强。现就BLBC的镜下特征、临床进展、预后及化疗反应等进行综述，便于临床及病理医师更好地认识这类疾病。
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| 关 键 词： | 乳腺肿瘤 癌 基底细胞 病理学 临床 |
| 收稿时间： | 2008-12-04; |
Clinicopathological characters of basal-like breast carcinoma |
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| YU Chang,NI Xing-hao. Clinicopathological characters of basal-like breast carcinoma[J]. Cancer Research and Clinic, 2009, 21(4): 282-285. DOI: 10.3760/cma.j.issn.1006-9801.2009.04.027 |
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| Authors: | YU Chang NI Xing-hao |
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| Affiliation: | YU Chang, NI Xing-hao( Department of Pathology, Zhejiang Cancer Hospital, Hangzhou 310022, China) |
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| Abstract: | Basal-like breast carcinoma is a phenotype of breast cancer which was sub-classified according to gene expression profiling criteria, associated with specific pathological features and biological behaviour. These cancer used to be more aggressive and characterized by the absent expression of ER/PR/CerbB-2(triple negative, TG) however positive for basal cytokeratins(basal CK). We present this review to show its pathological characters, clinical progression, prognosis and response to chemotherapy, and provide convenience for pathologists and surgical colleagues be more aware of this subtype. |
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| Keywords: | Breast neoplasms Carcinoma,basal cell Pathology,clinical |
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