基于四大中文数据库刊载地方性砷中毒研究的文献计量学分析

目的探索我国地方性砷中毒研究领域的动态,分析发展变化和趋势,为未来地方性砷中毒的研究提供借鉴。方法以中国期刊全文数据库(CJFD)、维普数据库(VIP)、中国生物医学文献光盘数据库(CBM disc)、万方资源数据库(WANFANG)为统计来源,时间限定为2008—2018年且主题词含"地方性砷中毒"及"地砷病"的文献。利用NOTE EXPRESS 2.0文献管理软件和EXCEL表格可视化分析纳入文献的发文期刊、基金分布、高频关键词和第一作者来源分布情况。结果共检索出科研论文1 941篇,纳入302篇,发文量总体呈逐年下降趋势,期间有小幅波动;刊载文献数量最多的期刊为《中华地方病学杂志》,共发文50篇(16.56%);82篇(27.15%)文献受到国家自然科学基金的资助;发文排名前七位的机构中哈尔滨医科大学位居首位;"砷中毒"、"地方性砷中毒"、"砷"、"饮水"与"煤"等为高频关键词,研究热点集中于从免疫学与基因学的角度研究砷中毒疾病的免疫毒性机制、从病因学角度分析砷中毒病区人群体内砷蓄积和砷代谢的差异与变化特征。结论近十年我国地方性砷中毒的文献逐年减少与疾病得到一定控制有关,国家及地方政府给予了一定的基金支持;应持续加强病区砷污染状况的监管,加强砷中毒疗法与药物研究,改善砷中毒病人的生命质量。

Bibliometrics analysis of research of endemic arsenism based on four Chinese journal databases

Objective To explore the status of research of endemic arsenism in China, analyze the development and trends,and provide references for future studies on endemic arsenism. Methods All literatures with key words of "endemic arseniasis" and published during 2008 to 2018 were collected from China Academic Journals Full-text Database(CJFD), VIP database, CBM disc and WANFANG DATA. The Note Express 2.0 document management software and EXCEL were taken to visually analyze the distribution of the published journals, fund, high-frequency keywords and the source of the first author.Results Out of the 1 941 retrieved papers, 302 were selected. The total number of publication showed decreasing trend in the latest ten years with slight fluctuations. The journal with the largest number of literatures was Chinese Journal of Endemiology(50 papers, accounting for 16.56%). All 82 papers(27.15%) were funded by National Natural Science Foundation of China. Harbin Medical University ranked the first among the top seven publishers."Arsenic poisoning","endemic arsenic poisoning","endemic arsenism","drinking water" and "coal" were the high frequency keywords. The researches were mainly concentrated on the immunotoxicity mechanism of arsenism in immunology and genetics, and the differences and changes of arsenic accumulation and metabolism inside the body of arsenism patient from the view of etiology. Conclusions The literatures of endemic arsenism research are decreasing in the latest ten years due to the disease being under control and certain financial support from local and national government. The supervision of arsenic pollution should be continuously strengthened in the epidemic area. Therapy and pharmaceutical research should be enhanced for improving quality of life of the patients.