原发女性乳腺癌术后生存率的改善

目的：女性原发乳腺癌术后生存率是否随时间进展有所改善，学术界曾有争论。一些学者认为有而另些则认为无。本文通过对天津肿瘤医院收治的乳腺癌进行回顾性研究。比较不同时期的生存率，并与欧美国家同期比较，企图说明天津肿瘤医院治疗乳腺癌技术不断提高，以及在国际所处的位置。方法：1954年至1984年间，天津肿瘤医院收治原发女性乳腺癌4491例，重新复习病历，按UIEC标准（1987）重新分期，全部病人随访5－15a，将病历资料输入计算机统计分析。结果：50年代，5a,10a和15a的生存率分别为48．4％，37．3％和30．8％；60年代为62．5％，50．9％和43．9％，70年代为69．9％、59．8％和50．7％，80年代仅有5a生存率为79．0％。结论：说明从50年代至80年代乳腺癌术后生存率明显提高。这一结果与美国白人及欧洲生存率最高的国家相同。

Improvement in survival of breast cancer with time

Objective: The improvement in survival of breast cancer patients with time has remained controversial. Some studies in recent decades have shown an improvement whereas others have shown no significant changes. This study was designed to compare the survival rate of women with breast cancer by various decades in Tianjin Cancer Hospital and compare it with Europe and American. Methods: Between 1954 and 1984, 4491 women with primary breast cancer were treated consecutively in Tianjin Cancer Hospital. All medical records of patients were reviewed. All tumors were re-staged according the criteria of UICC stage TNM classification(1987).Patients were followed for at least 5_15 years. All information was put into computer for analysis. Results: The five,ten and fifteen year survival rates in the 1950s were 48.4%, 34.3% and 30.8%, respectively; in the 1960s were 62.5%, 50.9% and 43.9%,respectively; in the 1970s were 69.9%, 59.8% and 50.7%, respectively; in the 1980s were 79.0%. Conclusion:The survival rates have increased from the 1950s to the 1980s. This result is comparable with EUROCART'S (11 countries in Europe) and the data of the American Cancer Society.