PET/CT鉴别诊断孤立性肺结节的优势与限度

目的：探讨PET/CT在孤立性肺结节（SPNs）鉴别诊断中的价值。方法：经病理证实的58例SPNs均行PET/CT扫描,结合结节的PET的代谢特点及CT的形态学特点综合判定SPNs的性质。结果：恶性SPNs的最大标准摄取值SUVmax（均值7.03±4.75）明显高于良性SPNs（均值2.06±1.06）,差异有统计学意义（t=6.40,P〈0.001）。PET/CT诊断恶性SPNs的敏感度、符合率、阴性预测值（100%、96.6%、100%）均较单独利用CT（88.2%、87.9%、50.0%）和单独利用PET（86.3%、84.5%、41.7%）高。结论：PET/CT可以提高诊断孤立肺结节的敏感度、符合率及阴性预测值。

The advantage and limitation of PET/CT in the differential diagnosis of solitary pulmonary nodule

Objective：To assess the value of PET/CT in the differential diagnosis of solitary pulmonary nodule（SPN）.Methods：58 patients with SPN underwent 18F-FDG PET/CT,the nature of SPN was diagnosed according to the metabolism feature of PET in combination with the morphology characteristics displayed on CT.All of the SPNs had pathology diagnosis.Results：The maximal standard uptake value（SUVmax） of malignant SPN（mean 7.03±4.75） was significantly higher than that of benign SPNs（mean 2.06±1.06）,with significant statistic difference（t=6.40,P0.001）.The sensitivity,accuracy,negative predictive value of PET/CT for malignant SPNs were 100%,96.6%,100% respectively,which was higher than that of using CT alone（88.2%,87.9%,50.0% respectively） as well as that of using PET alone（86.3%,84.5%,41.7% respectively）.Conclusions： The sensitivity,accuracy and negative predictive value in the diagnosis of SPN could be improved by PET/CT.