| 大肠癌组织中MMP-2、MMP-7的基因表达 |
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| 引用本文： | 朱民,姜金波,寿楠海.大肠癌组织中MMP-2、MMP-7的基因表达[J].中国现代普通外科进展,2004,7(6):358-359. |
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| 作者姓名： | 朱民 姜金波 寿楠海 |
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| 作者单位： | 山东大学齐鲁医院,普外科,山东,济南,250012 |
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| 摘 要： | 目的:观察MMP-2和MMP-7在大肠癌组织与正常组织中表达的差异.方法:取28例大肠癌组织及肿瘤周围正常组织,用RT-PCR方法检测肿瘤组织及正常组织中MMP-2和MMP-7的表达.结果:MMP-2和MMP-7在大肠癌组织中的表达率和表达水平高于周围的正常组织(P＜0.05).结论:MMP-2和MMP-7可能在大肠癌的进展中起重要作用.
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| 关 键 词： | 结直肠肿瘤·明胶酶A·基质溶解因子 |
| 文章编号： | 1009-9905(2004)06-0358-02 |
| 修稿时间： | 2004年2月23日 |
The expressions of MMP-2 and MMP-7 in colorectal cancer |
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| ZHU Min,JIANG Jin-bo,SHOU Nan-hai.The expressions of MMP-2 and MMP-7 in colorectal cancer[J].Chinese Journal of Current Advances in General Surgery,2004,7(6):358-359. |
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| Authors: | ZHU Min JIANG Jin-bo SHOU Nan-hai |
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| Institution: | ZHU Min,JIANG Jin-bo,SHOU Nan-hai Department of General Surgery,Qilu Hospital of Shandong University |
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| Abstract: | Objective: To investigate the expressions of MMP-2 and MMP-7 between colorectal cancer and normal tissue.Methods: RT-PCR was used to determine the expressions of MMP-2 and MMP-7 in colorectal cancer and normal tissue.Results: The expression rate and level of MMP-2 and MMP-7 were higher in cancerous tissue than that in normal tissue(P<0.05).Conclusion:MMP-2 and MMP-7 may play an important role in the progression of colorectal cancer. |
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