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奥利司他对肥胖IGT人群糖尿病预防效果
引用本文:韩英,江平,王治伟,梁灿炎. 奥利司他对肥胖IGT人群糖尿病预防效果[J]. 现代食品与药品杂志, 2004, 14(3): 40-41
作者姓名:韩英  江平  王治伟  梁灿炎
作者单位:广州港港湾医院,广州港防疫站,广州港港湾医院化验室,广州港港湾医院 内科,广州 510700,广州 510700,广州 510700
基金项目:广州市黄埔区科技项目(2002埔科13号)
摘    要:目的 探讨奥利司他(Orlistat,赛尼可)对肥胖糖耐量低减(IGT)患者的干预效果。方法 患者随机分两组奥利司他治疗组(50例)和对照组(51例),治疗为期1年,于治疗前后测量血脂、口服糖耐量试验(OGTT)、体重、身高等指标。结果1年后,治疗组上述指标明显改善(P<0.01),其恶化为糖尿病的发病率明显低于对照组(P<0.01)。结论 在肥胖IGT干预治疗中,奥利司他加饮食和运动治疗后可使体重减轻,改善糖耐量,明显减少糖尿病的发生。

关 键 词:肥胖  糖耐量低减  奥利司他  Orlistat
文章编号:1007-9939(2004)03-0040-02
修稿时间:2004-02-14

The preventive effect of Orlistat on the fatty IGT population from becoming diabetes mellitus
HAN Ying, JIANG Ping, WANG Zhi wei, LIANG Can yan Gangwan Hospital of Guangzhou Harbour,Guangzhou,Guangdong. The preventive effect of Orlistat on the fatty IGT population from becoming diabetes mellitus[J]. JOurnal of Modern Food and Pharmaceuticals, 2004, 14(3): 40-41
Authors:HAN Ying   JIANG Ping   WANG Zhi wei   LIANG Can yan Gangwan Hospital of Guangzhou Harbour  Guangzhou  Guangdong
Affiliation:HAN Ying, JIANG Ping, WANG Zhi wei, LIANG Can yan Gangwan Hospital of Guangzhou Harbour,Guangzhou,Guangdong,510700
Abstract:Objective To discuss the preventive effect of Orlistat on the fatty patients with impaired glucose tolerance (IGT). Meth-ods The patients, which had been divided into Orlistat group 50 cases socases and comparison group randomly 51 cases, were trealedfor one year. The index, such as blood-lipid, oral glucose tolerance test (OGTT), weight, height, etc. were measured before and afterthe treatment. Result After one year's treatment, the above index of Orlistat group were improved evidently(P < 0. 01), and the diabe-tes incidence of Orlistat group was much more lower than the comparison group (P<0.01). Conclusion On the treatment of fattyIGT, Orlistat with diet and exercise can loss weight, improve glucose tolerance, reduce diabetes incidence evidently.
Keywords:fatty  impaired glucose tolerance  orlistat
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