肝切除术治疗肝胆管结石316例报告

目的总结用肝切除术治疗肝内胆管结石的经验及评价其疗效。方法回顾性分析近20年间采用肝部分切除术治疗原发性肝内胆管结石316例的临床资料,统计结石的分布、术式选择、术后并发症及治疗效果。肝切除术式采用左外叶切除192例(60.76%),左半肝切除58例(18.35%),肝方叶切除12例(3.80%),右前叶切除6例(1.90%),右后叶切除25例(7.91%),右半肝切除9例(2.85%),双侧多区段肝切除14例(4.43%);其中附加胆肠内引流术184例(58.23%)、经肝实质切开取石4例。结果全组手术后发生并发症56例(17.72%),包括胆漏、胆道出血、膈下脓肿等。术后1个月内分别因应激性溃疡、肝肾衰竭、二重感染并多器官衰竭死亡各1例(0.95%)。258例获11个月至18年的随访,平均随访10.3年,优良率90.31%。结论规则性肝叶/段切除是治疗原发性肝胆管结石的有效手段。

Hepatectomy in the treatment of hepatolithiasis: a report of 316 cases

Objective To summarze our experience and evaluate the therapeutic effect of hepatectomy for intrahepatic bile duct stones. Methods The clinical data of 316 patients suffering from intrahepatic lithiasis who underwent hepatectomy from Feb. 1985 to Dec. 2004 were retrospectively analyzed. Stones distribution, operation modality, postoperative complications, and therapeutic effect were evaluated. Among the 316 patients, 192 cases(60.76%) were treated with left lateral hepatectomy, 58 cases(18.35%) with left hemihepatectomy, 12 cases(3.80%)with quadarate lobectomy, 54 cases(17.09%) with right hemihepatectomy or segmentectomy, and 14 cases(4.43%)with left and right segmentectomy. Additional biliary procedures including common bile duct exporation and cholangio-enterostomy were performed in 184 patients(58.23%). Results Postoperative complications occurred in 56(17.72%)cases, including biliary fistula, hemobilia, and subdiaphragmatic infections. Three patients(0.95%)died. The follow-up study conducted in 258 patients(81.65%)for an average of 10.3 years showed that excellent results were achieved in 90.31% of the patients. Conclusions Regular hepatic lobectomy/segmentectomy is the most effective treatment for intrahepatic lithiasis.