| 肺结核患者血清可溶性白细胞介素－2受体测定的研究 |
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| 引用本文： | 崔建军,范平,李均,管美英,袁光辉,黄其通. 肺结核患者血清可溶性白细胞介素－2受体测定的研究[J]. 中华结核和呼吸杂志, 1994, 0(5) |
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| 作者姓名： | 崔建军 范平 李均 管美英 袁光辉 黄其通 |
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| 作者单位： | 湖北医科大学附属第一医院，深圳市东湖医院，山西省长治市人民医院，山西省长治市妇幼保健院 |
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| 摘 要： | 采用酶联免疫吸附法检测了４０例初治菌阳肺结核患者和３０名健康人的血清可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）水平。其中对１８例患者于抗结核治疗１、２、３个月再次取血标本测定，并分析了ｓＩＬ－２Ｒ与病情变化的相关性。结果显示：肺结核患者的ｓＩＬ－２Ｒ水平治疗前为１２６６±９６２ｋＵ／Ｌ，治疗后３个月为５０７±１０８ｋＵ／Ｌ，与对照组（２３２±７２ｋＵ／Ｌ）相比均有显著性增高（Ｐ＜０．００１）。１８例患者ｓＩＬ－２Ｒ水平治疗前为１２５０±８９４ｋＵ／Ｌ，显著高于治疗后３个月的５０７±１０８ｋＵ／Ｌ（Ｐ＜０．００１）。治疗前患者血清ｓＩＬ－２Ｒ水平与病程、病变、空洞及治疗后与临床症状、病变、痰菌等有平行关系。这些结果提示ｓＩＬ－２Ｒ可作为肺结核诊断、病情监测及预后估计的一项参考指标。
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| 关 键 词： | 受体，白细胞介素2，结核，肺 |
Clinical significance of increased serum soluble inter-Iukin-2 recepter levels in patients with pulmonary tu-berculosis |
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| ChuiJianjun, FanPing, LiJun,et al.. Clinical significance of increased serum soluble inter-Iukin-2 recepter levels in patients with pulmonary tu-berculosis[J]. Chinese journal of tuberculosis and respiratory diseases, 1994, 0(5) |
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| Authors: | ChuiJianjun FanPing LiJun et al. |
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| Affiliation: | ChuiJianjun, FanPing, LiJun, et al. |
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| Abstract: | he serum soluble interleukin-2 receptor (slL-2R) was measured in 40 patients with pulmonary tu-berculosis by using sandwich enzyme linked im-munosorbent assay. The results show that the levelsof sIL-2R in sera of the various stage patients aremarkedly higher than that of the normal controls andthe serum levels of sILZR were associated significantly with the patients' conditions. These findings sug-gest that sIL-2R may be an useful referential indicatorfor diagnosing. monitoring and predicting pulmonarytuberculosis. |
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| Keywords: | Receptors interlukin-2 Tuber-culosis . pulmonary |
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