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Psychiatric disorders in temporal lobe gliomas
Authors:Lukshina A A  Urakov S V  Loshakov V A
Abstract:The rate of temporal lobe gliomas among all hemispheric glial tumors is up to 30%. Psychiatric disorders are typical for temporal lesions and could be even single manifestation of the disease. There is a rich variety of different psychopathologic and epileptic signs exactly in cases of temporal gliomas in comparison to tumors of other localizations. In our study we investigated psychiatric disorders on statistically significant group of patients (140 cases) with temporal lobe tumors with considerations of side, localization, histology of lesion and functional asymmetry of patients. We revealed psychiatric disorders in 72% of patients, mainly in glioblastoma. Seizures were more typical for WHO Grade I and II gliomas. Psychopathologic symptoms were more typical for left side lesions. Lefthanders had psychiatric disorders significantly more frequently than righthanders (p < 0.05). After surgical removal of tumor the rate of psychiatric disorders didn't differ statistically (p < 0.05) by 2 years follow-up. Complete regress of seizures was observe in 56% of cases.
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