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润肠通乐丸中何首乌的提取工艺研究
引用本文:吕倩,庞来祥,郭涛.润肠通乐丸中何首乌的提取工艺研究[J].现代中药研究与实践,2013(1):53-55.
作者姓名:吕倩  庞来祥  郭涛
作者单位:陕西中医学院;解放军第四五一医院
基金项目:全军医药卫生科研基金课题(11BJZ30)
摘    要:目的研究润肠通乐丸中何首乌的最佳提取工艺。方法采用正交试验设计,以乙醇浓度、溶剂用量、提取时间、提取次数为考察因素,以结合型蒽醌含量和80%乙醇浸出物为指标优选最佳提取工艺。结果最佳工艺为8倍量60%乙醇回流提取3次,每次1.5h。结论该工艺合理,稳定,可行,适合于润肠通乐丸中何首乌的提取。

关 键 词:润肠通乐丸  何首乌  结合型蒽醌  提取工艺

Study on Extraction Technology of Radix Polygoni Multiflori in Runchang tongle Pill
LU Qian,PANG Lai-xiang,GUO Tao.Study on Extraction Technology of Radix Polygoni Multiflori in Runchang tongle Pill[J].Research and Practice on Chinese Medicines,2013(1):53-55.
Authors:LU Qian  PANG Lai-xiang  GUO Tao
Institution:1.Shannxi University of Chinese Medicine,Xianyang 712046,China; 2.The 451th Hospital of PLA,Xi’an 710054,China)
Abstract:Objective To optimize the best extraction technology of Radix Polygoni Multiflori in Runchang Tongle Pill.Method Using four indexes including the ethanol concentration,solvent volume,extraction time and extraction times as the investigation factors,the content of bound anthraquinones and 80% ethanol soluble extraction was taken as the index for investigation,and then orthogonal design was adopted to select out the best alcohol extraction process.Result The best processing condition was as follows: adding 8 times amount of 60% ethanol and refluxing three times,1.5 h each time.Conclusion extraction of Radix Polygoni Multiflori by this method was reasonable,stable and feasible.
Keywords:Runchang Tongle Pill  Radix Polygoni Multiflori  Bound Anthraquinone  Extraction Technology
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