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Thyroid Hormone and Attention in School-Age Children with Congenital Hypothyroidism
Authors:Joanne Rovet  Miguel Alvarez
Affiliation:The Hospital for Sick Children, Toronto, Canada;National Institute of Neurology and Neurosurgery, Havana, Cuba
Abstract:The relationship between attention and thyroid hormone was examined using a retrospective database of 85 7-year-old children with congenital hypothyroidism who received psychological evaluations and thyroid function tests on the same day. Four unique subgroups with different levels of thyroxine and thyrotropin were compared on psychological tasks and measures of attention. Children with high levels of both hormones were found to be significantly more distractible on an index of cognitive attention but were reportedly less hyperactive. Level of thyroxine accounted for over 10% of the variance in attention.
Keywords:Thyroid hormone    attention    attention deficit disorder    congenital hypothyroidism    resistance to thyroid hormone
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