丙泊酚配伍芬太尼用于人工流产术524例的疗效观察

目的探讨丙泊酚配伍小剂量芬太尼麻醉用于人工流产术的效果,优选无痛人流最佳药物组合。方法选择早期妊娠患者524例,随机分为单纯丙泊酚组(Ⅰ组)和丙泊酚配伍芬太尼组(Ⅱ组)。观察患者的心率、收缩压、舒张压、动脉血氧饱和度,镇痛效果,清醒时间。结果2组孕妇诱导后60s及术中心率、收缩压、舒张压、动脉血氧饱和度值比较差异有统计学意义。镇痛效果,Ⅱ组比Ⅰ组好。呼吸抑制,Ⅰ组比Ⅱ组明显。Ⅰ组清醒时间与Ⅱ比较有统计学意义。结论丙泊酚配伍芬太尼静脉麻醉用于门诊无痛人工流产术是一种较为合理、安全可行的麻醉方法。

Clinical Observation on Application of Propofol Combined with Fentanyl to 524 Cases with Induced Abortion

Objective To explore the effects of propofol combined with a small dose of fentartyl in induced abortion and to optimize the best drug combinations to painless abortion. Methods 524 cases of early pregnancy were selected and randomly divided into pure propofol group（ group Ⅰ ）and propofol combined with fentanyl group（ group Ⅱ ）, the patients＇ heart rate, systolic blood pressure, diastolic blood pressure diastolic blood pressure, analgesic effects and awake time were observed. Results Heart rate, systolic blood pressure ,diastolic blood pressure, diastolic blood pressure had statistical significance between the two groups after inducing 60s and （luring operation. In analgesic effect,group Ⅱ is better than group Ⅰ. In respiratory depression,group Ⅰ is more obvious than group Ⅱ. In awake time,there was significant differenee between group Ⅰ and group Ⅱ. Conclusion The application of propofol combined with fentanyl intravenous anesthesia to painless artificial abortion in out-patient clinic is a more reachable, safe and more feasible anesthesia method.