巨块型早期宫颈癌复发COX多因素分析

[目的]探讨影响巨块型早期宫颈癌复发的危险因素。[方法]回顾性分析324例巨块型早期宫颈癌患者与复发相关的治疗和病理因素。[结果]全组复发率39.0%,5年生存率为62.5%。单因素分析显示新辅助化疗、病理分级、盆腔淋巴结转移、脉管侵犯、手术切缘癌细胞残留、深肌层癌细胞浸润、宫旁癌细胞浸润等与肿瘤复发关系密切(P<0.05)。COX多因素分析显示癌细胞分化程度低、深肌层癌细胞浸润和盆腔淋巴结转移是影响复发的主要危险因素(P<0.05)。[结论]巨块型早期宫颈癌的治疗需强调综合治疗,以减少复发。

Cox Regression Analysis of Factors Related to Recurrence of Bulky Early Stage Cervical Cancer

[Purpose] To investigate the recurrence risk factors in patients with bulky early stage cervical cancer. [Methods] The therapeutic and pathological factors related to recurrence in 324 cases with bulky early stage cervical cancer were analyzed retrospectively. [Results] The recurrence rate was 39.0% in this series and the 5-year survival rate was 62.5%. Univariate survival analysis showed that neoadjuvant chemotherapy, pathological grading, positive lymph nodes metastasis, vessel invasion, positive surgical...