| 薄层扫描法测定阴道栓中盐酸小檗碱的含量 |
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| 引用本文： | 刘强,李力,谭可.薄层扫描法测定阴道栓中盐酸小檗碱的含量[J].中国药房,2005,16(7):541-542. |
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| 作者姓名： | 刘强 李力 谭可 |
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| 作者单位： | 1. 第三军医大学大坪医院,重庆市,400042
2. 武警重庆总队卫生处,重庆市,401147 |
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| 摘 要： | 目的:建立阴道栓中盐酸小檗碱的含量测定方法。方法:以苯-醋酸乙酯-异丙醇-甲醇-水(6∶3∶1. 5∶1. 5∶0. 3)为展开剂,在紫外灯(365nm )下检视,另在薄层扫描仪上扫描,检测波长为430nm。结果:盐酸小檗碱进样量在0. 25μg～1 .25μg范围内线性关系良好(r=0. 9987) ,平均回收率为97 .63 % (RSD=1 .88 % )。结论:本方法简便、准确,可用于该制剂的质量控制。
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| 关 键 词： | 阴道栓 薄层扫描法 盐酸小檗碱 含量 |
| 文章编号： | 1001-0408(2005)07-0541-02 |
| 修稿时间： | 2004年6月28日 |
Content Determination of Berberine Hydrochloride in Pessums by TLC - scanning |
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| LIU Qiang,LI Li,Tan Ke.Content Determination of Berberine Hydrochloride in Pessums by TLC - scanning[J].China Pharmacy,2005,16(7):541-542. |
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| Authors: | LIU Qiang LI Li Tan Ke |
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| Abstract: | OBJECTIVE:To establish determine the content of berberine hydrochloride in the pessums.METHODS:Ben-zene-ethyl acetate-isopropanol-methanol-water(6∶3∶1.5∶1.5∶3)were taken as developers,which were detected under the UV light(365nm)and scanned by TLC scanner with the detective wavelength at430nm.RESULTS:The linear range of berberine hydrochloride on calibration curve was sample size0.25μg～1.25μg(r=0.9987),the average recovery rate was97.63%(RSD=1.88%).CONCLUSIONS:The method is simple,accurate and available for the quality control of pessums. |
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| Keywords: | Pessums TLC-scanning Berberine hydrochloride Content |
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