| 手术前后动态测定食管、贲门癌病人血清癌胚抗原水平的临床意义 |
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| 引用本文： | 周清华,杨俊杰,徐鹏,庞小捷,田子朴,伍佇,张怀斌,杨振华.手术前后动态测定食管、贲门癌病人血清癌胚抗原水平的临床意义[J].华西医学,1992(2). |
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| 作者姓名： | 周清华 杨俊杰 徐鹏 庞小捷 田子朴 伍佇 张怀斌 杨振华 |
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| 作者单位： | 华西医科大学附属第一医院，华西医科大学附属第一医院，四川垫江县人民医院，四川公路局医院，华西医科大学附属第一医院，华西医科大学附属第一医院，华西医科大学附属第一医院，华西医科大学附属第一医院 胸心外科，胸心外科，胸心外科，胸心外科，胸心外科，胸心外科 |
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| 摘 要： | 本实验运用放射免疫法检测了130例正常人,动态测定了110例食管、贲门癌和75例非癌胸疾病人手术前后血清癌胚抗原(CEA)水平。发现:食管、贲门癌病人CEA水平明显升高,其程度与病期、原发肿瘤大小、淋巴结转移、组织学类型和肿瘤分化程度等,有密切关系。本实验证明:食管、贲门癌病人切除肿瘤后,血清CEA从术后7天起逐渐降低,术后14天可达到或接近正常水平。术后14天CEA能达正常者,提示预后良好;反之,则预后不良。术后发生肿瘤转移时,血清CEA较术前成倍升高。
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| 关 键 词： | 癌胚抗原 食管 贲门癌 外科治疗 |
Clinical Importance of Sequential Study of the Level of Serum Carcinoembryonic Antigen (CEA) in Patients with Carcinoma of Esophagus and Cardia of stomach |
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| Zhou Qinghua,Yang Junjie,Xu Peng,Pang XiaoJie,Tian Zipu,Wu Zhu,Zhang Huaibin,Yang Zhenhua.Clinical Importance of Sequential Study of the Level of Serum Carcinoembryonic Antigen (CEA) in Patients with Carcinoma of Esophagus and Cardia of stomach[J].West China Medical Journal,1992(2). |
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| Authors: | Zhou Qinghua Yang Junjie Xu Peng Pang XiaoJie Tian Zipu Wu Zhu Zhang Huaibin Yang Zhenhua |
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| Institution: | Zhou Qinghua,Yang Junjie,Xu Peng,Pang XiaoJie,Tian Zipu,Wu Zhu,Zhang Huaibin,Yang Zhenhua. Department of Thoracic and Cardiovascular Surgery,The First University Hospital,West China University of Medical Sciences,Chengdu |
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| Abstract: | In this experiment, serial changes of the level of serum CEA were detected by ra- dioimmunoassay in carcinomas of no esophaus and cardia of stomach, and these tests were used to compare with those of 75 cases of noncancerous thoracic lesions and 130 normal adults.The results showed that the serum CEA in patients with cancers was significantly higher than that of noncancerous thoracic lesions and normal adults (P<0.01).The degree of elevation of serum CEA was closely related to the stages of cancer, the size of the primary tumor, the presence of lymph node metastasis, the types of histoclassification of tumor, and the differential degree of cancer.This study confirmed that the serum CEA decreased gradually from the 7th postoperative day on after the removal of the tumor and returned to normal level on the 14th postoperative day, indicating that these patients would have a good prognosis, on the opposite, their prognosis would be very poor.The serum CEA was doubled and redoubled than that before operation when metastasis occurred after operation. |
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| Keywords: | Carcinoembryonic Antigen Carcinoma of esophagus and cardia of stomach Surgical treatment |
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