Nd:YAG激光辅助牙周基础治疗的临床疗效分析

目的 采用Meta分析系统评价掺钕钇铝石榴石晶体激光（Neodymium-doped yttrium aluminium garnet,Nd:YAG）辅助牙周基础治疗的疗效。 方法 通过电子检索和手动检索中文发表的期刊文献、会议论文和学位论文，收集Nd:YAG激光辅助牙周基础治疗和单纯牙周基础治疗比较的临床研究资料。根据制定的纳入标准和排除标准，对纳入的文献研究进行质量评价、数据提取，并进行异质性检验和Meta分析，对得出的结果进行发表偏倚检验。 结果 共有8篇文献研究纳入本项Meta分析，其中5篇文献研究的观察指标为有效率，其余3篇的观察指标是牙周探诊深度、附着丧失和出血指数。结果显示Nd:YAG激光辅助牙周基础治疗在治疗后3个月时对牙周袋深度的改善效果明显，其余统计结果未见显著性差异，所有统计结果也未见明显的发表偏倚。 结论 Nd:YAG激光辅助牙周基础治疗在治疗后3个月时对牙周袋深度的改善效果明显，其余结果有待进一步研究论证。

Curative effect analysis of Nd:YAG laser assisting initial therapy of periodontal diseases

Objective To evaluate the effect of neodymium-doped yttrium aluminium garnet (Nd:YAG) laser assisting initial therapy of periodontal diseases by Meta-analysis. Methods The periodical literature,conference paper and academic dissertation of Chinese were scanned by electronic retrieval and manual search,and then the clinical studies which compared Nd:YAG laser assisting initial therapy of periodontal diseases to initial therapy of periodontal diseases alone were collected.According to inclusion and exclusion criteria,the quality assessment of these included studies,the data extraction were done and the heterogeneity test,the Mate-analysis were conducted.We also test the publication bias of the outcome by Meta-analysis. Results We adopted ultimately 8 studies into our research,of which the observation index was effective rate of 5 studies, while for remaining 3 studies the observation targets were PD(pocket depth),AL(attachment loss) and BI(bleeding index).There were no statistically significant differences in all the results of meta-analysis,except PD before and 3 months after SRP by Nd:YAG laser assisting initial therapy of periodontal diseases,accordingly no significant publication bias was found. Conclusions There was significant improvement in clinical efficiency on PD before and 3 months after SRP(scaling and root planning,SRP) by Nd:YAG laser assisting initial therapy of periodontal diseases,while the rest outcomes should be researched further patiently.