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阻塞性睡眠呼吸暂停综合征与血管内皮功能障碍研究进展
引用本文:傅坤发,陆甘,殷凯生. 阻塞性睡眠呼吸暂停综合征与血管内皮功能障碍研究进展[J]. 国际呼吸杂志, 2008, 28(20): 1277-1280
作者姓名:傅坤发  陆甘  殷凯生
作者单位:1. 江苏省省级机关医院老年科,南京,210024
2. 南京医科大学第一附属医院呼吸科,210029
摘    要:阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)是高血压、动脉粥样硬化等心血管疾病发病的重要危险因素之一,虽然目前机制尚未完全阐明,但与内皮功能障碍密切相关.本文就正常血管内皮功能、内皮功能障碍及评价方法 发、OSAHS与内皮功能障碍及治疗等进行综述.

关 键 词:睡眠呼吸暂停综合征  内皮功能障碍  心血管疾病

Advances in relationship between obstructive sleep apnea hypopnea syndrome and endothelial dysfunction
FU Kun-fa,LU Gan,YIN Kai-sheng. Advances in relationship between obstructive sleep apnea hypopnea syndrome and endothelial dysfunction[J]. International Journal of Respiration, 2008, 28(20): 1277-1280
Authors:FU Kun-fa  LU Gan  YIN Kai-sheng
Abstract:Obstructive sleep apnea hypopnea syndrome(OSAHS) is an important risk of adversecardiovascular consequences,including hypertension and atherosclerosis. While the mechanisms responsiblefor increased risk of cardiovascular events in OSAHS have not yet been fully elucidated, endothelialdysfunction may be a link between OSAHS and cardiovascular disease. This review will discuss normalendothelial function,endothelia dysfuntion and treatment in OSAHS.
Keywords:Obstructive sleep apnea syndrome  Endothelial dysfunction  Cardiovascular events
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