肾移植术后肺部严重感染病原学特征的探讨

目的 探讨肾移植术后引起严重肺部感染的病原学特征。方法 对28例肾移植术后肺部严重感染病例进行回顾性分析。结果 28例中有26例检出病原体，引起严重肺部感染的病原菌按出现频度高低依次为细菌(26例次，主要为肺炎克雷白杆菌、结核杆菌、绿脓杆菌、金黄色葡萄球菌、阴沟杆菌等)；病毒(8例次，主要为巨细胞病毒)；真菌(6例次，主要为白色念珠菌、热带念珠菌、青霉菌)。其中单纯感染12例，混合感染14例。结论 肾移植术后肺部严重感染的病原菌有其特定的菌群语，了解其规律对于临床及时准确治疗有重要意义。

Study on the etiology of the severe pulmonary infection in post-renal transplantation

Objective To explore the etiology of the severe pulmonary infection in post renal transplantation.Methods the clinical data of 28 patients with the severe pulmonary infection following kidney transplantation were retrospectively analyzed.Results Microorganisms could be detected in 26 cases out of 28 patients with the severe pulmonary infection in post renal transplantation.The main etiological causes according to their frequency and type were :bacteria (26 cases ,klebsiella friedlanderi,mycobacterium tuberculosis,pseudomonas,aureus staphylococcus,Bacillus cliacae,etc.);cytomegalovirus (8 cases);fungus (6 cases,candida albians,andida tropicals,penicillum patulum).46.1%(12/26)of the patients suffered from one organism ,and 53.9%(14/26) caused by mixed infection.Conclusion Characterized germ spectrum exists in the severe pulmonary infection in post renal transplantation and its role is important to clinical management.