老年住院患者FIB、APTT水平变化与下肢DVT的关系

目的 探讨老年住院患者纤维蛋白原(FIB)、活化部分凝血活酶时间(APTT)水平变化与下肢深静脉血栓形成(DVT)的关系.方法 选取本院108例老年住院患者,统计下肢DVT发生率及部位分布,将发生下肢DVT者作为研究组,未发生下肢DVT者作为对照组,对比两组临床资料及实验室指标,分析下肢DVT发生的影响因素,并探究FI...

Relationship between the changes of FIB and APTT levels in elderly hospitalized patients and DVT of lower limbs

Objective To investigate the relationship between fibrinogen(FIB)and activated partial thromboplastin time(APTT)levels in elderly hospitalized patients and deep vein thrombosis(DVT)of lower limbs. Methods 108 elderly inpatients in our hospital were selected,and the incidence and location distribution of DVT in lower limbs were counted. Patients with DVT of lower limbs were regarded as the study group,and those without DVT of lower limbs were regarded as the control group. The clinical data and laboratory indicators of the two groups were compared,and the factors affecting the occurrence of DVT in the lower limbs were analyzed. The correlation between FIB,APTT levels and APACHE Ⅱ scores was explored,and the diagnostic value of FIB,APTT levels and APACHE Ⅱ scores for DVT of lower limbs was analyzed.Results The incidence of DVT in the lower extremities of 108 elderly hospitalized patients was 13.89%,mainly the left lower extremity,accounting for 53.33%,the right lower extremity accounting for 33.33%,and both lower extremities accounting for 13.33%. The occurrence of DVT of lower limbs in elderly hospitalized patients was significantly correlated with age,length of stay,type of central venous replacement,APACHEⅡscore,FIB and APTT levels(P<0.05). The FIB and APTT levels of elderly hospitalized patients with DVT of lower limbs were positively correlated with APACHEⅡ score(r=0.714,0.635,P<0.05). The area under the curve(AUC)of FIB,APTT,and APACHEⅡ scores in the combined diagnosis of DVT of lower limbs was greater than that of each indicator alone,which was 0.859. Conclusion The significantly increased levels of FIB and APTT in elderly hospitalized patients are risk factors for DVT of lower limbs,and they have certain value in diagnosing lower limb DVT and evaluating the patient’s condition.