Method for assessing the stroke-to-stroke biomechanical characteristics of coronary vessels

The biomechanical parameters of coronary vessels are estimated in a model of the coronary input impedance. The model includes the capacity of epicardial vessels, input resistance, limiting resistance, and some sources of electromotive force symbolizing the intramyocardial and critical pressure values. The theoretical value of coronary blood flow is calculated from computer-optimized parameters of the model and experimental curves representing arterial pressure and left-ventricular pressure. The theoretical and experimental curves of coronary blood flow are in good agreement both during the maximum vasodilatation and in intact tone. The basic parameters, such as epicardial vessel pliability, zero blood flow pressure, and resistance of the resistive portion of blood vessels corresponded to previous evaluations. The dispersion of calculated stroke-to-stroke parameters is 5–10%. Translated from Byulleten'Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 11, pp. 594–597, November, 1996