羊膜移植治疗严重眼表面疾病的临床观察 |
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引用本文: | 赵敏,李鸿,周善壁,徐智勇,彭俊超. 羊膜移植治疗严重眼表面疾病的临床观察[J]. 重庆医科大学学报, 2001, 26(2): 166-168 |
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作者姓名: | 赵敏 李鸿 周善壁 徐智勇 彭俊超 |
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作者单位: | 重庆医科大学临床学院眼科 |
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摘 要: | 目的:研究羊膜移植治疗严重眼表面疾病的临床疗效。方法:对严重眼表面疾病29例31眼,其中急性眼烧伤炎症期6眼,陈旧性眼烧伤睑球粘连及其它眼表疾病25眼,施行单纯羊移植(15眼)和羊膜移植联合板层角膜移植术(16眼)随访3-18个月,平均8.4个月,结果:急性眼烧伤病变中4眼的炎症显著减轻。角膜未继续溶解,上皮修复;慢性病变中有20只眼的眼表面获得重建,睑球粘连得治愈或显著改善,视力不同程度提高。结论:对于急性严重的眼烧伤,羊膜移植能有效地阻止炎症和角膜溶解的发展,防止或减轻疤痕,对于陈旧性眼烧伤和其它眼表面疾病,羊膜是一种良好的生物学材料移植后能有效的重建眼表面。
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关 键 词: | 羊膜移植 眼表面疾病 化学烧伤 |
文章编号: | 0253-3626(2001)02-0166-03 |
修稿时间: | 2000-10-18 |
A clinical study on amniotic membrane transplantation for treatment of severe ocular surface disorders |
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Abstract: | Objective: To investigate the effect of amniotic membrane transplantation for severe surface disorders. Methods: Simple amniotic membrane transplantation 15 eyes and combined with lamellar keratoplasty 16 eyes were performed on severe ocular surface disorders ( acute ocular chemical and thermal burns 6 eyes, chronic ocular burn with severe symblepharon and other ocular surface disease 25 eyes). These patients were followed for 3-18 months ( mean 8.4 months). Results: The inflammation was decreased obviously in four out of six acute eye burns, no progressive corneal melting and perforation were seen . Ocular surface reconstruction was successful in 20 of 25 eyes with choronic ocular surface disorders. Symblepharon was cured or decreased. Visual acuity was improved in various degrees. Conclusion: Amniotic membrane transplantation can effectively reduce inflammation and block corneal melting in acute eye burn. As a good biologic material amniotic membrane can be used to reconstruct ocular surface for treating chornic ocular burn with symblepharon and other ocular surface diseases. |
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