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Fixed drug eruptions: a study of epidemiological, clinical and diagnostic aspects of 89 cases from India
Authors:V N Sehgal  O P Grangwani
Abstract:Fixed drug eruption incidence was 0.3% of outpatients. It affected individuals of both sexes in their 3rd and 4th decades, with a preponderance of males. Literary index and occupation were inconsequential. High index of suspicion for an etiologic drug was cardinal and was invariably supported by history. The clinical features of FDE were characteristic; it affected the upper and lower extremities, trunk, and lower lips. The diagnosis was confirmed by provocation test in 86 and cross-sensitivity in 11 patients. Analgesics and chemotherapeutic agents were primarily responsible for FDE in this population.
Keywords:fixed drug eruption  provocation test  cross-sensitivity  clinical features  causative drugs
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