少精及无精不育患者血清性激素水平分析

目的：探讨少精及无精不育患者血清性激素的水平及其临床意义.方法：对57例少精患者（少精组）及21例无精患者（无精组）进行精液分析,并取30名婚前要求进行精液检查的精子数量正常者作为对照组,采用放射免疫法测定3组患者血清睾酮（T）、促卵泡生成素（FSH）、促黄体生成素（LH）、垂体泌乳素（PRL）的水平.结果：无精组与少精组血清中FSH、LH水平均高于对照组（P ＜0.05～P＜0.01）;而无精组FSH、LH水平又均明显高于少精组（P＜0.01）;无精组PRL水平均较对照组及少精组升高（P＜0.01）;而无精组和少精组血清T水平均明显低于对照组（P＜0.01）.结论：对少精症及无精不育患者血清生殖激素的测定有助于指导诊断、治疗以及预后.

Analysis of sex hormone levels of infertile males with oligospermia or azoospermia

Objective： To investigate the sex hormone levels of infertile males with oligospermia or azoospermia and its clinical significance. Methods ：The semen of 57 cases with oligospermia（ oligospermia group）,21 cases with azoospermia（ azoospermia group） and 30 cases with rormal sperm count（ control group） were analysed. The serum levels of testosterone（T） ,follicle stimulating hormone （FSH）, luteinizing hormone （LH） and prolactin （P） of all cases were determined by ehemiluminescent immunoassay. Results：The levels of FSH and LH in the azoospermia and oligospermia group were higher than that in control group（ P 〈 0.05 - P 〈 0.01 ）. The FSH and LH levels of the azoospermia group were significantly higher than that in oligospermia group（ P 〈 0.01 ）. The level of PRL in azoospermia group was higher than those in the control and oligospermia group （ P 〈 0. 01 ）. The T levels of the azoospermia and oligospermia group were significantly lower than that in control group （P 〈 0. 01 ）. Conclusious：The serum levels of sex hormone of infertile males with oligospermia or azoospermia can help guide diagnosis and treatment and prognosis.