和田地区维吾尔族2型糖尿病酮症酸中毒复发患者的特点分析

目的：探讨新疆和田地区维吾尔族2型糖尿病酮症酸中毒（DKA）复发患者的特点和原因.方法：分析和田地区37例维吾尔族和16例汉族DKA复发患者的病历资料.统计年龄、性别、糖尿病病程、入院时的血糖、糖化血红蛋白（HbA1c）、血压、血总胆固醇、三酰甘油（TG）、高密度脂蛋白、低密度脂蛋白、血尿素氮（BUN）、肌酐、pH值和二氧化碳结合力（CO2CP）、血肌酸激酶（CK）等指标,并进行分析.结果：维吾尔族DKA患者的病程、HbA1c、TG、BUN、CK、pH、CO2 CP与汉族DKA患者差异均有统计学意义（P ＜0.05～P＜0.01）.维吾尔族DKA患者的酮体转阴时间、pH值恢复正常时间、每天胰岛素用量和住院时间均大于汉族DKA患者（P ＜0.05～P＜0.01）.维吾尔族糖尿病患者的饮食控制差于汉族患者（P＜0.01）.结论：维吾尔族的DKA复发患者的病情比汉族更重、恢复更慢.要重视维吾尔族DKA的临床特点,有针对性地强化和田地区糖尿病患者的宣教、饮食指导才能改善和田地区糖尿病控制不佳的现状.

Analysis of recurrent ketoacidosis in Uighur patients with type 2 diabetes in hotan region

Objective：To study the characteristics and reasons of recurrent diabetic ketoacidosis（DKA） in Uighur patients with type2 diabetes in Xinjiang hotan region.Methods：The clinical data of 37 Uighur and 16 Han patients with recurrent DKA in hotan area were analyzed.The patients＇ age,genders,course of the disease,blood glucose levels,glycosylated hemoglobin A1c （HbAlc） levels,blood pressure,blood total cholesterollevels,triglyceride （TG） levels,high density ripoprotein,low density lipoprotein,blood urea nitrogen（BUN）,creatinine,pH,carbon diaxide combining powere （CO2 CP）,and serum creatine kinase （CK） were collected and analyzed.Results：There were significant differences between the two groups in the course of DKA,HbA1c,TG,BUN,CK,pH and CO2CP（P ＜ 0.05 to P ＜ 0.01）.The recovery time of ketone,pH,insulin dosage every day and the hospital stay of the Uighur diabetes group exceeded those of the Han patients group（P ＜ 0.05 to P ＜ 0.01）.The alimentary control in Uighur diabetes group was poorer than that in Han patients group （P ＜ 0.01）.Conclusions：The condition of recurrent DKA is more serious in Uighur diabetes patients than in Han patients,and the recovery is slower.The characteristics of recurrent uygur DKA should be considered and the diabetes diet guidance strengthened in hotan area.Only in this way,can the poor control of diabetes in the area be improved.