爱西特保留灌肠治疗慢性肾衰竭短期疗效观察

目的探讨爱西特保留灌肠治疗慢性肾衰竭的疗效.方法62例慢性肾衰竭(CRF)氮质血症期患者随机分为两组:对照组30例,常规口服爱西特治疗;治疗组32例,常规口服爱西特加爱西特保留灌肠.观察两组治疗过程中病情演变,治疗前后血清尿素氮(BUN)、肌酐(Scr)、尿酸(UA)及内生肌酐清除率(Ccr)的水平.结果治疗后两组BUN、Scr、UA及Ccr均有显著性差异(P＜0.05).结论口服爱西特加爱西特保留灌肠治疗CRF疗效显著优于单纯口服爱西特组.

Observation of Ai Xi Te on treating patients with chronic renal failure

Objective: To investigate the effect of retention enema of Ai Xi Te on treating patients with chronic renal failure. Methods: 62 patients with chronic renal failure were divided into two groups randomly. 30 patients in the control group were treated with oral Ai Xi Te as routine method; 32 patients in the therapy group were treated with retention enema of Ai Xi Te and routine method. To observe the charge of clinical manifestation, the concentration of Bun, Scr, UA and Ccr in serum were measured before and after therapy. Results: The concentration of Bun, Scr, UA and Ccr in serum after therapy displayed significantly lower in therapy group than that of control group(P<0.05). Conclusion: The retention enema of Ai Xi Te displays significantly better effect than routine oral method on treating patients with chronic renal failure.