| 阿司匹林抵抗在脑梗死二级预防中与血管事件的关系 |
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| 引用本文： | 郜晓飞. 阿司匹林抵抗在脑梗死二级预防中与血管事件的关系[J]. 中国现代医生, 2014, 0(3): 34-36 |
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| 作者姓名： | 郜晓飞 |
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| 作者单位： | 河南省登封市人民医院神经内科,河南登封452470 |
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| 摘 要： | 目的探讨阿司匹林抵抗在脑梗死二级预防中与血管事件的关系。方法选择脑梗死患者200例为研究对象,患者入院后就口服阿司匹林治疗,服用1周后通过检测血小板聚集率检测患者是否出现阿司匹林抵抗,并对患者进行随访,观察患者脑梗死复发以及其他血管时间发生率,分析阿司匹林抵抗与血管事件发生的相关性。结果单因素分析结果显示,女性、低密度脂蛋白(LDL)升高、糖尿病是发生阿司匹林抵抗的预测因素(P<0.05)。糖尿病、LDL升高是阿司匹林抵抗的危险因素,糖尿病、阿司匹林抵抗、动脉硬化血栓型梗死是血管事件的危险因素(P<0.05或P<0.01)。结论阿司匹林抵抗在脑梗死二级预防中是血管事件的危险因素。
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| 关 键 词： | 阿司匹林 脑梗死 抵抗 二级预防 血管事件 |
Relationship between aspirin resistance and vascular events for secondary prevention of cerebral infarction |
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| GAO Xiaofei. Relationship between aspirin resistance and vascular events for secondary prevention of cerebral infarction[J]. , 2014, 0(3): 34-36 |
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| Authors: | GAO Xiaofei |
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| Affiliation: | GAO Xiaofei Department of Neurology, Dengfeng People＇s Hospital in Henan Province, Dengfeng 452470, China |
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| Abstract: | Objective To discuss the relationship between aspirin resistance and vascular events for secondary prevention of cerebral infarction. Methods Selected 200 cases with cerebral infarction who were treated by aspirin. Aspirin resistance was detected at 7 days after treated. Relationship between aspirin resistance and vascular events for sec- ondary prevention of cerebral infarction was analyzed. Results Single factor analysis showed that female, high level of LDL, diabetes mellitus were risk factors of aspirin resistance （P 〈 0.05）. Multiple-factor analysis showed that high level of LDL, diabetes mellitus were risk factors of aspirin resistance, and diabetes mellitus, aspirin resistance, arteriosclero- sis thrombosis infarction were risk factors of vascular events （P 〈 0.05 or P〈0.01）. Conclusion Aspirin resistance is risk factor of vascular events in secondary prevention of cerebral infarction. |
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| Keywords: | Aspirin Cerebral infarction Resistance Secondary prevention Vascular events |
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