| 口腔颌面部恶性肿瘤患者外周血中NK细胞数目的测定 |
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| 引用本文： | 周会喜,赵建江,李梅,许曼波. 口腔颌面部恶性肿瘤患者外周血中NK细胞数目的测定[J]. 广东牙病防治, 2002, 10(4): 255-256 |
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| 作者姓名： | 周会喜 赵建江 李梅 许曼波 |
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| 作者单位： | 广东省口腔医院,广东,广州,510280 |
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| 摘 要： | 目的：测定口腔颌面部恶性肿瘤患者外血周中NK细胞数目。方法：对19例口腔癌患者及对照组11例正常清晨抽取外周血，用流式细胞仪进行分析，测定NK细胞数目。结果：肿瘤患者外周血中的NK细胞数目明显低于对照组（P＜0．01）；不同分化程度的恶性肿瘤患者外周血中的NK细胞数目也有显著差异。结论：外周血中的NK细胞与恶性肿瘤的生物学行为有一定的关系，对其检测，对临床具有指导意义。
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| 关 键 词： | 口腔颌面部 恶性肿瘤 外周血 NK细胞 流式细胞仪 临床意义 |
Detection of NK cells Number in Peripheral Blood of Patients with Malignant Tumour in Oral and Maxillofacial Regions |
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| Zhou huixi,et al,Guangdong Provicial Stomatological Hospital,Guangzhou. Detection of NK cells Number in Peripheral Blood of Patients with Malignant Tumour in Oral and Maxillofacial Regions[J]. Journal of Dental Prevention and Treatment, 2002, 10(4): 255-256 |
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| Authors: | Zhou huixi et al Guangdong Provicial Stomatological Hospital Guangzhou |
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| Affiliation: | Zhou huixi,et al,Guangdong Provicial Stomatological Hospital,Guangzhou 510280 |
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| Abstract: | Objective To study the number of NK cells in peripheral blond of patients with malignant tumor in oral and maxillofacial regions. Result The samples of peripheral blood from 19 patients with malignant tumours in oral and maxil-lofacial regions and 11 healthy persons were detected by flow cytometry. Reult The number of NK cells in peripheral blood showed significant difference (P<0. 01) between the patients with malignant tumours and the healthy persons. So did the different degeneration of malignant tumours (P<0.01). Conclusions These finds suggested that the difference of NK cells number in peripheral blood be related to the biological behaviors of malignant tumours. It also may be an important prognostic indication of malignant tumours in oral and maxillofacial regions. |
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| Keywords: | Natural killer cell Oral and maxillofacial region Malignant tumours |
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