重度子痫前期患者子宫动脉及胎儿脐动脉的血流动力学变化

目的 观察分析重度子痫前期母儿血液动力学变化特点,结合其母儿预后,探讨母儿血流动力学监测在重度子痫前期的临床诊治及预后估计中的应用价值.方法 应用彩色多普勒超声检测73例重度子痫前期和81例正常同期孕妇的胎儿脐动脉的收缩末期最大血流速度和舒张末期最大血流速度之比(S/D)、搏动指数(PI)、阻力指数(RI)及子宫动脉的S/D、PI、RI,并结合其预后进行统计分析.结果 重度子痫前期患者的脐动脉S/D、PI、RI值均高于对照组,子宫动脉的S/D、PI、RI值也均高于对照组,差异有统计学意义(P<0.05).当重度子痢前期出现母胎血流动学变化时,围生儿不良结局的发生率高于正常妊娠组.结论 子痫前期患者存在子宫动脉及脐动脉阻抗增高、血供不足,这些病理生理变化与不良妊娠结局相关.

Changes of hemodynamics in the maternal uterine artery and fetal umbilical artery of patients with severe pre-eclampsia

Objective To observe the characteristic of hemodynamics in the maternal uterine artery and fetal umbilical artery of patients with severe pre-eclampsia(S-PE),combined with the prognosis,to evaluate the value of hemodynamics monitor in clinical diagnosis and treatment.Methods A prospective study was conducted in 73 patients with severe pre-eclampsia and 81 healthy pregnant women.Color Doppler blood flow visualize technology was used to detect the systolic to diastolic velocity ratios(S/D),pulsatility indices...