18F-FDG PET/CT在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值

目的：评估18F氟脱氧葡萄糖正电子发射断层显像（18F-FDGPET/CT）在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值。方法回顾性分析57例宫颈癌患者病历资料，将治疗前18F-FDGPET/CT检查结果与术后病理结果进行比较。结果宫颈癌原发灶18F-FDGPET/CT检查阳性55例，阴性2例，诊断敏感度96．5％（55/57）。22例经手术治疗患者中，9例（9/22，40．9％）经手术病理证实盆腔淋巴结转移。18F-FDGPET/CT诊断宫颈癌盆腔淋巴结转移的敏感度、特异度、准确度、阳性预测值和阴性预测值分别为66．7％（6/9）、92．3％（12/13）、81．8％（18/22）、85．7％（6/7）、80．0％（12/15）。结论18F-FDGPET/CT诊断宫颈癌原发灶具有极高的敏感度，能有效地检出宫颈癌原发灶；诊断宫颈癌盆腔淋巴结转移特异度较高，但敏感度一般，特别是短径＜1．0cm淋巴结。

18F FDG PET/CT in Diagnosis of Primary Cervical Cancer and Pelvic Lymph Node Metastasis

Objective To evaluate the clinical value of 18 F-fluorodeoxyglucose positron emission tomography （18 F-FDG PET/CT ） in the diagnosis of primary cervical cancer and pelvic lymph node metasta-sis . Methods The clinical data of 57 patients with cervical cancer were retrospectively analyzed . All patients underwent 18 F-FDG PET/CT scanning pretherapy . The diagnostic results of 18 F-FDG PET/CT were compared with postoperative pathological findings . Results Of the 57 patients with pathologically confirmed cervical cancer ,18 F-FDG PET/CT was positive in 55（55/57 ,96 .5% ）patients and negative in 2 （2/57 ,3 .5% ）patients in the primary lesion . The sensitivity of 18 F-FDG PET/CT was 96 .5% （55/57） . In with 22 patients who underwent surgical treatment ,9（9/22 ,40 .9% ） were confirmed pelvic lymph node metastasis by postoperative pathological findings . T he sensitivity ,specificity ,accuracy ,positive predic-tive value and negative predictive value of 18 F-FDG PET/CT in detect the pelvic lymph node metastasis w ere 66 .7% （6/9 ） ,92 .3% （12/13 ） ,81 .8% （18/22 ） ,85 .7% （6/7 ） ,80 .0% （12/15 ） ,respectively . Conclusions 18 F-FDG PET/CT has a high sensitivity in diagnosis of the primary lesion of cervical cancer , it can effectively detect primary tumors ;in pelvic lymph node metastasis ,the diagnosis specificity of this method is high ,but sensitivity is moderate ,especially the short diameter ＆lt;1 .0 cm lymph nodes .