| 硫氰化铬铵在药物比色分析上的应用 Ⅱ.抗疟药奎宁、优奎宁、乙胺嘧啶、磷酸氯喹、磷酸伯氨喹及其片剂的测定 |
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| 引用本文： | 盛曙光,叶崇义,彭司勋. 硫氰化铬铵在药物比色分析上的应用 Ⅱ.抗疟药奎宁、优奎宁、乙胺嘧啶、磷酸氯喹、磷酸伯氨喹及其片剂的测定[J]. 药学学报, 1965, 12(10): 662-666 |
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| 作者姓名： | 盛曙光 叶崇义 彭司勋 |
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| 作者单位： | 江苏省卫生厅药品检验所,南京;南京药学院 |
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| 摘 要： | 本文报告了奎宁、优奎宁、乙胺嘧啶、磷酸氯喹、磷酸伯氨喹及其片剂的硫氰化铬铵剩余试剂比色法。对沉淀生成与介质pH值的关系,沉淀的组成及比色测定的浓度范围等进行了系统研究。应用本法测定了上述药物及其片剂的平均回收率为99.96%,相对平均偏差为±0.20%,并与药典方法进行了比较,结果符合。
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| 收稿时间： | 1964-12-21 |
COLORIMETRIC DETERMINATION OF ANTIMALARIAL DRUGS AND THEIR TABLETS BY MEANS OF AMMONIUM REINECKATE |
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| SHENG SHE-GUON YE CHONG-YI. COLORIMETRIC DETERMINATION OF ANTIMALARIAL DRUGS AND THEIR TABLETS BY MEANS OF AMMONIUM REINECKATE[J]. Acta pharmaceutica Sinica, 1965, 12(10): 662-666 |
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| Authors: | SHENG SHE-GUON YE CHONG-YI |
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| Abstract: | A method for colorimetric determination of quinine salts (euquinine, pyrimethamine, chloroquine phosphate, and primaquine phosphate) is described. The principle of the method is based on measuring the absorbances of excess reagent after removal of insoluble reineckate salts. The molecular composition of the reineckates at various pH (1-8) and the optimum condition for the determination were studied. The average deviation of the method proposed is ±0.20%. |
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