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Isoenzyme characterization of Leishmania braziliensis braziliensis isolates obtained from Bolivian and Peruvian patients.
Authors:S Revollo  L Dimier-David  C David  P Lyevre  C Camacho  J P Dedet
Affiliation:Instituto Boliviano de Biología de Altura, c/o Embajada de Francia, Bolivia.
Abstract:Thirty-four Leishmania isolates obtained from Bolivian and Peruvian patients infected with mucocutaneous leishmaniasis were characterized by isoenzyme electrophoresis using 10 enzymatic markers; all belonged to the subspecies L.b. braziliensis. Three isolates showed marked variation compared with the reference strain with respect to 5 or 6 enzymes. These variant isolates originated from patients with forms of the disease which were unresponsive to treatment.
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