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Effect of Saikokeishito,a Kampo medicine,on hydrogen peroxide-induced premature senescence of normal human dermal fibroblasts
Institution:1. Medical Research Institute of Kanazawa Medical University, Ishikawa, Japan;2. Department of Medical Oncology, Kanazawa Medical University, Ishikawa, Japan;3. Department of Nephrology, Kanazawa Medical University, Ishikawa, Japan;1. National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, People’s Republic of China;2. Department of Breast Surgery, Harbin Medical University, Cancer Hospital, Harbin 150040, People’s Republic of China;3. Department of Biomedical Engineering, 4 Colby Street, Tufts University, Medford, MA 02155, USA;4. The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, Soochow University, Suzhou, People’s Republic of China;1. Department of Surgery, Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA;2. Department of Anesthesia, Center of Head and Orthopedics, Copenhagen University Hospital, Copenhagen, Denmark;3. Department of Surgery, University of Ann Arbor Hospital, Ann Arbor, MI;4. Division of Vascular Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, Boston, MA;5. Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA;6. Section for Transfusion Medicine, Copenhagen University Hospital, Copenhagen, Denmark;7. Department of Surgery, University of Texas Health Science Centre at Houston, Houston, TX;1. BRD School of Biosciences, Vadtal Road, Satellite Campus, Post Box No 39, Sardar Patel University, Vallabh Vidyanagar 388 120, Gujarat, India;2. Department of Biotechnology, Shree A.N. Patel PG Institute, Sardar Patel University, Anand 388 001 Gujarat, India;3. The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA;1. Department of Surgery, Teikyo University, Tokyo, Japan;2. Department of Cardiovascular and Thoracic Surgery, the 4th Affiliated Hospital of Harbin Medical University, Harbin, China;3. Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan;4. Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, China
Abstract:
Keywords:Saikokeishito  medicine  Kampo  premature senescence  p53  fibroblasts
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