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Management of geriatric mania complicated by hyponatremia and psychogenic adipsic hypernatremia
Affiliation:1. Department of Psychiatry, Government Medical College, Aurangabad, Maharashtra, India;2. Department of Internal Medicine, Citicare Superspeciality Hospital, Aurangabad, Maharashtra, India;3. Institute of Human Behaviour and Allied Sciences (IHBAS), New Delhi, India
Abstract:A 70-year-old male presented with first episode mania and hyponatremia, which were later corrected with an infusion of hypertonic saline. His clinical condition deteriorated because of adipsic hypernatremia associated with hypokalemic periodic paralysis. Hypernatremia correction and potassium supplementation were started but could not be achieved because of manic symptoms as the patient's oral intake was poor. He was restarted on sodium valproate and olanzapine. Over the next few days, the patient's manic symptoms improved significantly and oral intake improved, which eventually led to correction of hypernatremia. Clinicians should evaluate the existence of electrolyte imbalance while dealing with a case of geriatric mania.
Keywords:Adipsic hypernatremia  Geriatric mania  Hyponatremia  Sodium valproate
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