Evaluation of the nutritional status in older patients with aggressive haematological malignancies using the MNA-SF |
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| Affiliation: | 1. Department of Geriatrics, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium;2. Department of Haematology, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium;1. Unit and School of Geriatrics, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria n. 1, 98125 Messina, Italy;2. Unit and School of Nephrology, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria n. 1, 98125 Messina, Italy;3. Department of Experimental Pathology and Microbiology, University of Messina, Via Consolare Valeria n. 1, 98125 Messina, Italy;1. National Institute of Health Research (NIHR) Biomedical Research Centre, Guy''s and St Thomas’ NHS Foundation Trust and King''s College London, London, United Kingdom;2. Guy''s and St Thomas’ NHS Foundation Trust, St Thomas’ Hospital, Lambeth Palace Road, London SE1 7EH, United Kingdom;3. Institute of Gerontology, Department of Social Science, Health and Medicine, School of Social Science and Public Policy, King''s College London, Strand London WC2R 2LS, United Kingdom;1. Institute for Genome Sciences & Policy and Sanford School of Public Policy, Duke University, Durham, USA;2. Institute for Genome Sciences & Policy, Duke University, Durham, USA;3. Departments of Medicine, Psychiatry, and Nursing, Duke University, Center for Health Services Research in Primary Care, Durham VAMC, Durham, USA;1. Ouro Preto Federal University (UFOP), School of Nutrition, Ouro Preto, Minas Gerais, Brazil;2. Institute of Food Technology (ITAL), Center of Foods Science and Quality, Campinas, São Paulo, Brazil;1. Department of Geriatric Medicine, Diakonessenhuis Utrecht-Zeist-Doorn, Professor Lorentzlaan 76, 3707 Zeist, The Netherlands;2. Department of Geriatric Medicine, Rijnland Hospital, Leiderdorp, The Netherlands;3. Department of Geriatric Medicine, Tweestedenziekenhuis, Tilburg, The Netherlands;4. Department of Surgery, Diakonessenhuis, Utrecht, The Netherlands;5. Department of Internal Medicine, Haga hospital, Den Haag, The Netherlands;6. Department of Internal Medicine, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands;1. Unit of Primary Health Care, Helsinki University Central Hospital and Department of General Practice and Primary Health care, University of Helsinki, P.O. Box 20 (Tukholmankatu 8 B), 00014 Helsinki, Finland;2. National Institute for Health and Welfare, Mannerheimintie 166, 00271 Helsinki, Finland;3. Social Services and Health Care Department, City of Helsinki, Toinen linja 4 A, 00530 Helsinki, Finland |
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| Abstract: | BackgroundMalnutrition is common both after the age of 70 and in many types of cancer, being responsible for poor quality of life, poor treatment response and a shorter survival time. Patients with haematological malignancies face specific challenges regarding nutrition because of intensive treatments they endure. Early detection of nutritional problems is important to allow interventions.ObjectivesTo assess the nutritional status of a group of older patients with aggressive haematological malignancies before the onset of systemic therapy using the MNA-SF.SettingThe haematology department of a university hospital.ParticipantsPatients ≥ 70 years, with newly diagnosed aggressive haematological malignancies.MethodsObservational single centre study. Patients were screened for malnutrition before and two months after start of therapy using the Mini Nutritional Assessment Short Form (MNA-SF).ResultsSeventy patients were included. Mean age was 77.4 ± 4.7 years (range 70.0–91.0). At baseline, 20% (CI95 = 11–31%) were malnourished and 61% (CI95 = 49–73%) were at risk for malnutrition. Recent weight loss and declined food intake were the most recorded MNA-SF parameters. Mean Body Mass Index (BMI) was 26.3 ± 4.1 (range 19.8–41.1) and 41% (n = 29) of patients had a BMI < 25.ConclusionsUsing the MNA-SF, most of the older patients with an aggressive haematological malignancy are at risk for malnutrition. Therefore, nutritional assessment with individualised dietary advice and follow-up during treatment should be recommended as an integrated part of the treatment plan. |
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| Keywords: | Aged Haematological neoplasm MNA-SF Malnutrition Nutrition assessment |
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