JCL Roundtable: HDL in the primary care setting |
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| Institution: | 1. Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, Texas;2. Health Policy, Quality & Informatics Program, Michael E. DeBakey Veterans Affairs Medical, Center Health Services Research and Development Center for Innovations, Houston, Texas;3. Department of Pharmacotherapy & Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, Virginia;4. Center for Cardiovascular Analytics, Research and Data Science (CARDS), Providence Heart Institute, Providence St. Joseph Health, Portland, Oregon;5. Section of Cardiology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas;6. Center for Cardiovascular Disease Prevention, Methodist DeBakey Heart and Vascular Center, Houston, Texas;7. Section of Health Services Research, Department of Medicine, Baylor College of Medicine, Houston, Texas;8. Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois |
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| Abstract: | One of the most difficult and confusing issues for clinical lipidologists and physicians in general has been the management of low concentrations of high-density lipoprotein cholesterol. We know this to be a very powerful predictor of risk in scores of community-based and clinical trial cohorts. Raising this number in many patients would seem to provide a great therapeutic opportunity, but so far this concept has been very difficult to prove. I have been joined for this discussion by a cardiovascular epidemiologist, Dr. Rachel Mackey, from the University of Pittsburgh and two clinical lipidologists who have studied and written in depth about this problem. These are Dr. Benjamin Ansell from the University of California in Los Angeles and Dr. Peter Toth from Johns Hopkins University School of Medicine. Our objective in this discussion is to give primary care clinicians our thoughts about the recent research findings and the implications of these data on the best clinical practice. |
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| Keywords: | HDL cholesterol HDL-C Primary care Cardiovascular disease Metabolism |
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