Malnutrition in elderly patients with renal failure: Importance of pre-dialysis period |
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| Affiliation: | 1. Department of Nephrology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey;2. Department of Internal Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey;3. Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey;4. Nephrology, Turkish Kidney Foundation, Istanbul, Turkey;1. Diabetes Center, Aizawa Hospital, Matsumoto, Japan;2. Rehabilitation Center, Aizawa Hospital, Matsumoto, Japan;3. Data Science, Clinical Research Department, Kissei Pharmaceutical, Tokyo, Japan;4. Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan;5. Ohike Clinic, Matsumoto, Japan;6. Toba Clinic, Chikuhoku, Nagano-prefecture, Japan;7. Yazaki Clinic, Azumino, Japan;8. Yokoyama Clinic, Yamagata, Nagano-prefecture, Japan;9. Suzuki Clinic, Matsumoto, Japan;10. Shironishi Hospital, Matsumoto, Japan;11. Division of Diabetes, Endocrinology and Metabolism, Shinshu University School of Medicine, Matsumoto, Japan;12. Department of Nephrology, Shinshu University School of Medicine, Matsumoto, Japan;1. Department of Neurology, Kanta-Häme Central Hospital, Ahvenistontie 20, 13130 Hämeenlinna, Finland;2. Medical School, Tampere University, Tampere, Finland;3. Department of Neurosurgery, Tampere University Hospital, Tampere, Finland;4. Research Unit, Pirkanmaa Hospital District, Tampere, Finland;5. Tampere School of Public Health, University of Tampere, Tampere, Finland;6. Department of Pharmacy, University of Eastern Finland, Kuopio, Finland;7. Science Service Center, Kuopio University Hospital, Kuopio, Finland;8. National Institute for Health and Welfare, Helsinki, Finland;1. Hyonam Kidney Laboratory, Soon Chun Hyang University, Seoul, Korea;2. Baxter Novum and Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden;3. Kim''s Clinic and Dialysis Unit, Miryang, Korea;1. Division of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan;2. The Graduate Institute of Clinical Medical Sciences, Chang Gung University Medical College, Taoyuan School of Medicine, Taoyuan, Taiwan;3. College of Medicine, Chang Gung University, Tao-Yuan, Taiwan;4. Community Medicine Research Center, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan;5. Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan;6. College of Medicine, Taipei Medical University, Taipei, Taiwan;7. Department of Nursing, Ching Kuo Institute of Management and Health, Taiwan;8. Heart Failure Research Center, Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan;9. Department of Nursing, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan;10. Department of Nutrition, Chang Gung Memorial Hospital, Keelung, Taiwan;11. Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan;12. Laboratory for Epidemiology, Department of Health Care Management, Chang Gung University, Taoyuan, Taiwan;13. Department of Emergency Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan;14. Department of Urology, Chang Gung Memorial Hospital, Taoyuan, Taiwan |
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| Abstract: | Background and aimsIn elderly, renal failure is one of the major comorbidities. Malnutrition is another clinical problem in these patients’ follow-up. In this study, we compared nutritional states of elderly patients with different renal functions.MethodsEighty-three predialysis and 121 hemodialysis (HD) patients of 65 years and older and as control group, 46 elderly patients with no renal failure were compared. Blood urea nitrogen, creatinine, thyroid stimulating hormone, vitamin B12 and folic acid levels were measured in every patient. Nutritional status of all patients was evaluated with Mini Nutritional Assessment Short Form (MNA-SF). One-way ANOVA, post-hoc Tukey and Pearson correlation analysis were used for statistics.ResultsThe mean MNA-SF of pre-dialysis patients was 8.67 ± 3.00. In HD patients, it was 11.44 ± 2.43 and in control, it was 11.48 ± 2.27. In HD patients, a weak correlation was detected between higher BUN, creatinine and higher MNA-SF (r = 0.181, P = 0.047), (r = 0.181, P = 0.046). In HD patients, vitamin B12 levels were higher than pre-dialysis and control group (P < 0.001).ConclusionIn elderly patients with renal failure, malnutrition starts in pre-dialysis period and MNA-SF can be a reliable technic for these patients’ nutritional evaluation. |
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| Keywords: | Elderly Hemodialysis Nutrition MNA-SF Pre-dialysis |
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