| 坦索洛辛在输尿管镜碎石术治疗输尿管下段结石中的作用 |
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| 引用本文： | CAO Zhengguo,诸禹平,SHU Hong,吴斌,SUN Youwen,董晓程.坦索洛辛在输尿管镜碎石术治疗输尿管下段结石中的作用[J].临床泌尿外科杂志,2008,24(6). |
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| 作者姓名： | CAO Zhengguo 诸禹平 SHU Hong 吴斌 SUN Youwen 董晓程 |
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| 作者单位： | 安徽医科大学附属省立医院泌尿外科,合肥,230001 |
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| 摘 要： | 目的:评价α1-受体阻滞剂(坦索洛辛)在经尿道输尿管镜碎石术治疗输尿管下段结石中的临床作用.方法:将符合条件的79例输尿管下段结石患者随机分为坦索洛辛 URSL组和单纯URSL组,两组患者年龄、性别、结石最大直径等差异均无统计学意义.单纯URSL组采用常规经尿道输尿管镜钬激光碎石术(URSL),坦索洛辛 URSL组术前连续服用坦索洛辛0.2 mg/d,2周后再行URSL.结果:坦索洛辛 URSL组只有1例中转开放手术,输尿管镜碎石成功率高达97.5%(39/40),高于单纯URSL组79.5%(31/39)(χ2=4.688,P=0.030),手术和术后住院时间分别为(13.33±4.42)min和(2.54±0.99)天,均短于单纯URSL组(19.19±6.60)min和(3.26±0.93)天(t=4.081,P=0.000;t=3.092,P=0.003),肾绞痛发生率分别为70.0%(28/40):89.7%(35/39)(χ2=4.766,P=0.029].结论:经尿道输尿管镜钬激光碎石术联合坦索洛辛治疗输尿管下段结石能显著提高输尿管镜碎石成功率,缩短手术时间和住院时间,缓解肾绞痛发生.
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| 关 键 词： | 坦索洛辛 输尿管镜碎石术 输尿管结石 |
Role of tamsulosin in management of lower ureteral calculi before ureteroscopic holmium laser lithotripsy |
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| CAO Zhengguo,ZHU Yuping,SHU Hong,WU bing,SUN Youwen,DONG Xiaocheng.Role of tamsulosin in management of lower ureteral calculi before ureteroscopic holmium laser lithotripsy[J].Journal of Clinical Urology,2008,24(6). |
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| Authors: | CAO Zhengguo ZHU Yuping SHU Hong WU bing SUN Youwen DONG Xiaocheng |
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| Institution: | 1Department of Urology;Anhui Provincial Hospital Affiliated to Anhui Medical College;Anhui;230001;China |
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| Abstract: | Objective:To evaluate the potential role of alpha-1 receptor blocker(tamsulosin) in management of lower ureteral calculi before ureteroscopic holmium laser lithotripsy.Methods:79 patients with symptomatic lower ureteral calculi were enrolled and randomly divided to control group and tamsulosin treatment group.No significant differences were found between two groups for age,gender distribution and maximum stone diameter.The control group was routinely treated by transureteroscopic holmium laser lithotripsy(U... |
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| Keywords: | Tamsulosin Ureteroscopic lithotripsy Lower ureteral calculi |
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