Recovery after anaesthesia for pulmonary surgery: desflurane, sevoflurane and isoflurane |
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Authors: | Dupont J; Tavernier B; Ghosez Y; Durinck L; Thevenot A; Moktadir-Chalons N; Ruyffelaere-Moises L; Declerck N; Scherpereel P |
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Institution: | Department d'Anesthesie Reanimation Chirurgicale II, CHRU, Lille, France; C.H.R. Hopital de Warquignies Boussu, Belgique |
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Abstract: | We have studied maintenance and recovery profiles after general anaesthesia
with sevoflurane, desflurane and isoflurane in 100 patients undergoing
pulmonary surgery. End-tidal concentrations of anaesthetic required to
maintain mean arterial pressure and heart rate within 20% of baseline
values were 1.4 +/- 0.6% for sevoflurane, 3.4 +/- 0.9% for desflurane and
0.7 +/- 0.3% for isoflurane. The three anaesthetics had comparable
haemodynamic effects and arterial oxygenation during one- lung ventilation.
Emergence was twice as fast with desflurane than with sevoflurane or
isoflurane (mean times to extubation: 8.9 (SD 5.0) min, 18.0 (17.0) min and
16.2 (11.0) min for desflurane, sevoflurane and isoflurane, respectively).
Early recovery (Aldrete score, cognitive and psychomotor functions) was
also more rapid after desflurane. In pulmonary surgery, desflurane, but not
sevoflurane, allowed more rapid emergence and earlier recovery than
isoflurane.
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