| Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis简 |
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| 引用本文： | ZHENG Lu,ZHOU Yuan,ZHANG Jia-Yu,SONG Min,YUAN Ye,XIAO Yan-Jiao,XIANG Ting. Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis简[J]. 中国天然药物, 2014, 0(2): 142-147 |
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| 作者姓名： | ZHENG Lu ZHOU Yuan ZHANG Jia-Yu SONG Min YUAN Ye XIAO Yan-Jiao XIANG Ting |
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| 基金项目： | This project was supported by the Science and Technology Achievement Transformation Project of Jiangsu Province （No. BA2010144）; and the scientific and technological maj or special project for ＂Significant Creation of New Drugs＂ （No. 2012ZX09101231）. |
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| 摘 要： | AIM： To investigate the chemical constituents of Dioscorea zingiberensis C. H. Wright. METHODS： The compounds were isolated by various chromatographic techniques, and the structures of the new steroidal sapon- ins were elucidated by extensive 1D- and 2D-NMR, MS, and IR spectral analysis. RESULTS： The 70% EtOH extract of the rhizomes of Dioscorea zingiberensis afforded two new steroidal saponins, zingiberenosides A （1） and B （2）, along with eight known analogues, 3fl, 26-dihydroxy-25（R）-furosta-As＇ 20（22）-diene-3-O-a-L- rhamnopyranosyl-（1→2）-O-β-D-glucopyranoside （3）, methyl parvifloside （4）, deltoside （5）, methyl deltoside （6）, zingiberensis new saponin （7）, deltonin （8）, progenin III （9） and diosgenin-diglucoside （10）. CONCLUSION： Two new steroidal saponins were isolated from Dioscorea zingiberensis and their structures determined.
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| 关 键 词： | Dioscorea zingiberensis Dioscoreaceae Steroidal saponins Zingiberenoside |
Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis |
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| ZHENG Lu,ZHOU Yuan,ZHANG Jia-Yu,SONG Min,YUAN Ye,XIAO Yan-Jiao,XIANG Ting. Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis[J]. Chinese JOurnal of Natural Medicines, 2014, 0(2): 142-147 |
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| Authors: | ZHENG Lu ZHOU Yuan ZHANG Jia-Yu SONG Min YUAN Ye XIAO Yan-Jiao XIANG Ting |
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| Affiliation: | [1]Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China; [2]School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100029, China |
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