栓皮栎茎叶化学成分的分离与鉴定

目的研究栓皮栎(Quercus variabilis Blume)茎叶的化学成分。方法用硅胶、Sephadex LH-20柱色谱等方法进行分离纯化,根据理化性质及NMR谱学数据确定化合物的结构。结果分离得到10个化合物,分别鉴定为羽扇豆酮(lupeone,1)、lup-20(29)-en-3β,30-diol(2)、3α-羟基木栓烷-2-酮(3α-hydroxyfriedel-2-one,3)、熊果酸(ursolic acid,4)、齐墩果酸(oleanolic acid,5)、槲皮素(querce-tin,6)、山柰酚(kaempferol,7)、木犀草素(luteolin,8)、金丝桃苷(hyperoside,9)、没食子酸(gallic acid,10)。结论化合物1~10均为首次从该植物中分离得到。

Isolation and identification of chemical constituents from stems and leaves of Quercus variabilis Blume

Objective To study the chemical constituents of the stems and leaves of Quercus variabilis Blume. Methods The compounds were isolated by repeated silica gel and Sephadex LH-20 chromatographies. The structures of the compounds isolated were identified by physico-chemical properties and spectral analysis. Results Ten compounds were isolated and their structures were identified as lupeone(1), lup-20(29)-en-3β,30-diol(2), 3α-hydroxyfriedel-2-one(3), ursolic acid(4)，oleanolic acid(5), quercetin(6), kaempferol(7), luteolin(8), hyperoside(9) and gallic acid(10). Conclusions Compounds 1-10 are obtained from this plant firstly.