The incidence and structure of congenital anomalies at the Maternity Home State University Hospital, Sofia in the period of 1992-1996

This is a retrospective study on the dynamics of inborn malformations in University Hospital of Obstetrics and Gynaecology 'Ma?chin Dom', Sofia for a five-years-long period of time (1992-1996). The results show that the rate of inborn anomalies in the discussed period of time remains approximately the same, while there is an increase of the relative part of heavy and life-threatening malformations. They cause death of nearly half of term infants who die in the neonatal period. These facts lead to the conclusion that to decrease perinatal and neonatal mortality, early and exact prenatal diagnosis of inborn malformations is absolutely necessary.