肾上腺醛固酮腺瘤术后临床转归的影响因素

肾上腺醛固酮腺瘤是原发性醛固酮增多症的一种常见类型,一般对单侧肾上腺醛固酮腺瘤的治疗方案是进行手术切除.经手术治疗可以降低高血压,影响术后血压恢复的因素有年龄、高血压持续时间、肾功能、基因型和醛固酮受体拮抗剂敏感,但也可以在术后并发高钾血症和慢性肾脏疾病,引起术后发生高钾血症的因素有高血压持续时间和肾小球滤过率,引起术后发生慢性肾脏疾病的因素有术前肾小球滤过率和醛固酮肾素比值.因此,应该对单侧肾上腺醛固酮腺瘤手术治疗的患者进行全方面的评估,以避免术后并发症的发生.

Influence factors of postoperative clinical outcomes for patients with adrenal aldosteronoma

Adrenal aldosteronoma is one of the common types of primary aldosteronism and the treatment of unilateral adrenal aldosterone tumor is surgical resection.Surgical treatment can reduce blood pressure.The influence factors of postoperative blood pressure are age, duration of high blood pressure, kidney function, genotype and sensitivity of aldosterone receptor antagonist.But surgery can also be complicated with hyperkalemia and chronic kidney disease.Hyperkalemia occurred after surgery greatly influenced by factors of high blood pressure and glomerular filtration rate.Postoperative chronic kidney disease greatly influenced by the factors of preoperative glomerular filtration rate and aldosterone renin ratio.Therefore, patients with unilateral adrenal aldosteronoma need all aspects of evaluation before surgery, in order to avoid the occurrence of postoperative complications.