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Endoscopic Submucosal Dissection Combined with the Placement of Biodegradable Stents for Recurrent Esophageal Cancer After Chemoradiotherapy
Authors:Yosuke Mochizuki  Yasuharu Saito  Toyohiko Tanaka  Norihisa Nitta  Hirokazu Yamada  Tomoyuki Tsujikawa  Kiyoshi Murata  Yoshihide Fujiyama  Akira Andoh
Affiliation:(1) Division of Digestive Endoscopy, Department of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu 520-2192, Japan;(2) Division of Mucosal Immunology, Graduate School of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, Japan;(3) Department of Radiology, Shiga University of Medical Science, Seta-Tukinowa, Otsu, Japan;(4) Department of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, Japan;(5) Kyoto Medical Planning Co. Ltd, Yamashina, Kyoto, Japan;
Abstract:We report a case of a patient with esophageal squamous cell carcinoma who presented with obstruction of the esophagus. On endoscopy, a central ulcerating lesion was found spreading to the anterior wall of the middle esophagus. Four courses of chemoradiation therapy successfully produced a complete response for 3 years. A recurrence occurred which consisted of a morphologically flat lesion that occupied the entire circumference of the esophagus. Endoscopic submucosal dissection removed all lesions en bloc. To prevent a post-procedure mucosal defect of the circumference of the esophagus, biodegradable poly-l-lactic acid monofilaments esophageal stents were placed on the same day. One month later, the patient reported a feeling of obstruction. An endoscopic examination revealed food stuck in the stents, this was removed, and balloon dilatation provided good passage which has been maintained for 7 months.
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