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N末端脑钠肽前体在维吾尔族心力衰竭中的诊断价值
引用本文:左继岩,茶春喜,罗仁,杜晓强,陈劢,姚建平,艾克拜尔,杨胜祥,梁田,禹新华. N末端脑钠肽前体在维吾尔族心力衰竭中的诊断价值[J]. 临床和实验医学杂志, 2011, 10(4): 249-251
作者姓名:左继岩  茶春喜  罗仁  杜晓强  陈劢  姚建平  艾克拜尔  杨胜祥  梁田  禹新华
作者单位:1. 石河子大学医学院,新疆,石河子,832002
2. 兵团农一师医院暨石河子大学第四附属医院心内科,新疆,阿克苏,843000
摘    要:目的探讨检测维吾尔族心力衰竭(CHF)患者血浆N末端脑钠肽前体(NT-proBNP)水平的临床意义。方法 78例维吾尔族心衰患者根据纽约心脏病协会(NYHA)分级标准分为心功能Ⅰ级(A组8例),Ⅱ级(B组19例),Ⅲ级(C组23例)及Ⅳ级(D组28例)4组,健康对照组51例。用电化学发光法检测NT-proBNP血浆浓度,心脏彩超检测其射血分数。结果心衰患者血浆NT-proBNP水平明显高于正常对照组[(6 329.7±4 697.4比77.9±53.8)pg/m l,P<0.001];不同NYHA心功能分级患者的血浆NT-proBNP浓度比较,可见两者随心功能级别增加而显著升高,且与汉族相同心功能分级无显著性差异。结论血浆中NT-proBNP水平可判断患者是否存在心衰可能;可作为维吾尔族患者心功能不全的检测指标,可判断心衰严重程度及指导临床治疗的指标。

关 键 词:维吾尔族  慢性心力衰竭  N端脑钠肽前体

Diagnostic value of plasma NT-proBNP in Uigur patients with chronic heart failure
ZUO Ji-yan,CHA Chun-xi,LUO Ren,et al.. Diagnostic value of plasma NT-proBNP in Uigur patients with chronic heart failure[J]. Journal of Clinical and Experimental Medicine, 2011, 10(4): 249-251
Authors:ZUO Ji-yan  CHA Chun-xi  LUO Ren  et al.
Affiliation:ZUO Ji-yan1,CHA Chun-xi2,LUO Ren2,et al.1 Medical College,Shihezi Uiversity,Shihezi Xinjiang 832002,China,2 Department of Cardiology,the Fourth Affiliated Hospital of Medical College,Shihezi University,Akesu Xinjiang 843000
Abstract:Objective To explore the clinical significance of plasma N-terminal pro-brain natriuretic peptide(NT-proBNP) in patients of Uigur with chronic heart failure(CHF).Methods Seventy-eight Uigur patients with CHF and 51 healthy subjects were investigated.Based on New York Heart Association(NYHA) grading criterion,the patients were divided into four groups: group A(8 cases),group B(19 cases),group C(23 cases) and group D(28 cases).NT-proBNP was determined by electrochemiluminescence.Cardiac function was evaluated...
Keywords:Uigur  Chronic heart failure  N-terminal pro-brain natriuretic peptide  
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